Who we are
Why we built mOI
More than twenty years ago, my co-founder Dan and I caught the same bacterial infection. I recovered. He developed debilitating reactive arthritis.
Our genetics help explain why. Dan carries HLA-B27, a variant that increased his risk. It showed us how genetics can provide powerful context for our health, and is one reason mOI offers Whole Genome Sequencing.
I've also watched my mother-in-law Myrto struggle with rheumatoid arthritis and Sjögren's, dismissed and underserved by a system that wasn't built for complexity.Two people I love. Different diseases. Years of uncertainty.
We built mOI so more people can understand what's happening in their body, be heard when something isn't right, and have the support they need to find their way forward.
Understand what's going on
Your immune system needs balance, not boosting
It shapes how you feel day to day. Your energy.
How often you get ill. How your body responds and recovers.
Yours could be working too hard, or not hard enough.
Most people can't tell if their immune system is overreacting or underperforming.
mOI is designed to give you answers and solve these problems.
When your immune system is overactive
Joint pain, chronic fatigue, rashes, gut problems, or allergies keep showing up. Your immune system has gone into attack mode.
When your immune system is underactive
You get sick easily, recover slowly, or feel exhausted no matter how much you rest. Your immune system is struggling to protect you.
Built by people who understand
Our founding team combines clinical research expertise and lived experience with immune conditions. We know what it's like to face conflicting test results, feel like you are not being seen and the exhausting reality of trying everything but obtaining no clear answers.
Our team
Scientific advisors
Research from our advisers
Work by the people who advise us, spanning immunology, genomics and inflammatory disease. This is their research, not ours.
The Human Cell Atlas
A map of every cell type in the human body, and the reference much of modern immunology is now read against.
Teichmann et al.Mutational signatures in human cancer
How patterns in a genome reveal what caused the damage, and the method behind clinical genome interpretation.
Nik-Zainal et al.Genetic risk and outcome in inflammatory bowel disease
Why two people with the same diagnosis can have very different disease.
Lee et al.Innate immunity and inflammaging
When we’re chronically inflamed, our bodies are primed for dysfunction and disease.
Bryant et alThe pathogenesis of rheumatoid arthritis
Rheumatoid arthritis is a chronic autoimmune disease that causes progressive articular damage, functional loss, and comorbidity.
McInnes et alWhat we are working on
Our own assay programme, in plain terms, with what is proven and what is not. Placeholder: links to Research in Resources once that section exists.